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Fig. 5 | Genome Biology

Fig. 5

From: iRegNet3D: three-dimensional integrated regulatory network for the genomic analysis of coding and non-coding disease mutations

Fig. 5

Mutations across interacting chromatin regions cause diseases by potentially disrupting TF-mediated chromatin looping. a Schematic diagram of two mutations across interacting TF regions located at the same type of TF binding motif, and causing the same disease. b Schematic diagram of two mutations across interacting TF regions located at two binding motifs of TFs that interact with each other, causing the same disease

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