Table 1 Details of discarded diagnostic samples from patients used in the study. The numbers in parentheses indicate the number of patients in each group

EBOV-positive samples for RNA-seq (n = 138)

Poor quality: removed from analysis (n = 26)

N/A

N/A

Good-quality samples (n = 112)

Survived (n = 24)

Transcriptomic analysis for differential gene expression and classifier generation

Fatal (n= 88)

EBOV-positive and malaria-negative (n = 37)

N/A

Fatal (n = 20)

Flow analysis

Survived (n = 17)

Febrile and EBOV-negative (n = 10)

N/A

N/A

Malaria-positive and EBOV-negative (n = 5)

N/A

N/A

EBOV-positive sample with similar Ct values (n = 20)

Good quality (n = 20)

Survived (n = 10)

Validation dataset for differential gene expression and classifiers

Fatal (n = 10)

Convalescent EBOV-negative (n = 16)

Good quality (n = 16)

Survived (n = 16)

Control for EBOV-positive samples

Healthy controls (n = 6)

Good quality (n = 6)

Never infected (n = 6)

Comparator for convalescent samples