|
EBOV-positive samples for RNA-seq (n = 138)
|
Poor quality: removed from analysis (n = 26)
|
N/A
|
N/A
|
|
Good-quality samples (n = 112)
|
Survived (n = 24)
|
Transcriptomic analysis for differential gene expression and classifier generation
|
|
Fatal (n= 88)
|
|
EBOV-positive and malaria-negative (n = 37)
|
N/A
|
Fatal (n = 20)
|
Flow analysis
|
|
Survived (n = 17)
|
|
Febrile and EBOV-negative (n = 10)
|
N/A
|
N/A
|
|
Malaria-positive and EBOV-negative (n = 5)
|
N/A
|
N/A
|
|
EBOV-positive sample with similar Ct values (n = 20)
|
Good quality (n = 20)
|
Survived (n = 10)
|
Validation dataset for differential gene expression and classifiers
|
|
Fatal (n = 10)
|
|
Convalescent EBOV-negative (n = 16)
|
Good quality (n = 16)
|
Survived (n = 16)
|
Control for EBOV-positive samples
|
|
Healthy controls (n = 6)
|
Good quality (n = 6)
|
Never infected (n = 6)
|
Comparator for convalescent samples
|
