Skip to main content

Table 1 Ten most nominally significant probes from a bivariate GREML analysis testing genetic correlations that deviate from r G=1

From: Autosomal genetic control of human gene expression does not differ across the sexes

Probe Chr. Position Gene \(h^{2}_{\text {mal}}\) \(h^{2}_{\text {fem}}\) r G SE P
ILMN1713006 19 492686-492735 CDC34 0.68 0.64 0.36 0.14 8.45×10−6
ILMN2383058 20 1610083–1610132 SIRPG 0.68 0.54 0.27 0.15 3.54×10−5
ILMN1710017 17 59361234–59361283 CD79B 0.62 0.64 0.32 0.14 3.59×10−5
ILMN1796165 14 95080536–95080585 GLRX5 0.76 0.66 0.47 0.13 4.44×10−5
ILMN1715169 6 32654825–32654845 HLA-DRB1 0.94 0.86 0.72 0.08 1.23×10−4
ILMN1723520 1 156494456–156494505 CD1A 0.38 0.60 0.001 0.19 1.26×10−4
ILMN1675483 2 241418872–241418921 ANKMY1 0.67 0.70 0.53 0.13 1.64×10−4
ILMN1742001 1 145696009–145696058 CD160 0.70 0.67 0.42 0.13 1.75×10−4
ILMN1776998 15 76361232–76361281 DNAJA4 0.51 0.66 0.36 0.16 2.05×10−4
ILMN1662451 19 7659893–7659942 FCER2 0.74 0.70 0.47 0.13 2.15×10−4
  1. No probes satisfied the Bonferroni corrected significance threshold of P=3.99×10−6. The parameters \(h^{2}_{\text {mal}}\) and \(h^{2}_{\text {fem}}\) represent the estimated heritability for males and females, respectively
  2. Chr. Chromosome