Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing

Table 3 Single-cell sequencing-based classification versus morphologic classification

		Morphologic classification
		TC	Uncertain	PHC	HC	Total
Sequencing-based classification	DTC	10	-	-	1	11
	AU	3	3 (+1)	7 (+1)	1 (+2)	14 (+4)
	N	6	5	5	-	16
	Doublets	5^a	3^a	1^a	1 (+2)	10^a (+2)
	Total	24	11 (+1)	13 (+1)	3 (+4)	51 (+6)

^aSome of these doublets contain a DTC (see also Additional file 1: Figures S7 and S8 and Additional file 2: Table S6). Control cells are counted between brackets. DTC disseminated tumor cell, AU aberrant cell of unknown origin, N normal cell, TC tumor cell, Uncertain uncertain cell, PHC probable hematopoietic cell, HC hematopoietic cell.