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Table 1 Clinical parameters of the six breast cancer patients

From: Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing

Patient

Histology

Grade

pN status

HR status

Her2 status

PAM50 subtype

Systemic recurrence (time to recurrence or last observation)

Age at diagnosis (years)

Time to death (months)

Disease status

MicMa003

ILC

2

2

Pos

Neg

LumA

Yes (11.71 months)

36

-

Alive (241 months)

MicMa017

ILC

2

1

Pos

Neg

LumA

No (last obs 80.98 months)

78

80.98

Dead other cause

MicMa019

IDC

2

2

Pos

Neg

LumB

Yes (40.31 months)

71

52.56

Dead BrCa

MicMa044

IDC

2

ND

Neg

Pos (FISH)/neg (IHC)

Basal

No (last obs 8.26 months)

81

8.26

Dead other cause

MicMa083

ILC

2

3

Pos

Neg

LumA

Yes (11.21 months)

69

19.37

Dead BrCa

MicMa107

ILC

2

3

Pos

Neg (FISH)/pos (IHC)

LumB

Yes (44.31 months)

45

55.10

Dead BrCa

  1. BrCa breast cancer, ER estrogen receptor, FISH fluorescence in situ hybridization, HR hormone receptor, IDC invasive ductal carcinoma, IHC immunohistochemistry, ILC invasive lobular carcinoma, LumB luminal B, ND not determined, Neg negative, Obs observation, pN axillary lymph node involvement, Pos positive