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Fig. 1 | Genome Biology

Fig. 1

From: Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing

Fig. 1

DNA copy number profiles of breast tumors and bone marrow-derived single cells. ag Per patient profiles are shown as concentric circles inside the circular human karyogram. Total (clonal) copy number is represented as a heat map from blue to red as indicated. Tumor samples and single cells are labeled on the corresponding circles and are color-coded: primary tumor bulk (PT) in cyan, lymph node bulk (LN) in purple, DTCs in orange, aberrant cells of unknown origin in dark green, and normal cells in green. Cells isolated after MOPC 21 isotype control staining are boxed. Panels are shown for patient MicMa003 (a), MicMa017 (b), MicMa019 (c), MicMa044 (d), MicMa083 (e), and MicMa107 at the time of diagnosis (f) and 3 years post-diagnosis (g)

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