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Table 1 Highest-ranking genes for association with LZD resistance MICs ≥ 128 μg/mL

From: Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary

Gene Comment OR p Pairwise p Accession Reference
cfr cfr-family 23S ribosomal methyltransferase 18 0.0089 0.0156 - 0.1093 AGJ70604 [33]
pinE DNA recombinase (pLRSA417-associated) Inf 0.0038 0.03125 - 0.03125 EXP54287 [34]
cueR HTH-type transcriptional regulator Inf 0.0123 0.03125 - 0.03125 AJM87290 [34]
Mergeda Presumed plasmid genes Inf 0.0123 0.0625 - 0.0625 - -
blaR1 Beta-lactamase regulatory protein 0.067 0.0237 0.0625 - 0.3125 WP_001096374 [35]
Hypo. Hypothetical protein Inf 0.0350 0.0625 - 0.0625 - -
  1. P values < = 0.05 in italics
  2. aYolD-like protein, TrbC/VIRB2-family protein, seven hypothetical proteins
  3. OR odds ratio, p naïve p value, Pairwise p range of p values from the pairwise comparisons, Emp p empirical p value after 1000 permutations