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Fig. 3 | Genome Biology

Fig. 3

From: Patterns of ribosomal protein expression specify normal and malignant human cells

Fig. 3

Differential expression of RPs is conserved across evolutionarily distant vertebrates. a RP expression was examined for five different vertebrates (rhesus macaque, mouse, rat, cow, and chicken) that have diverged ~300 million years ago. b, c RP mRNA expression levels in testis (b) and skeletal muscle (c) compared to the average expression levels across all tissues in five different vertebrates. Each dot is an RP gene, and the linear fit is shown as a dotted line. RPs displaying significant tissue-specific expression are shown in orange and labeled. Increased expression of RPL10 and RPL39L in testis is conserved in human, rhesus macaque, mouse, and rat. RPL10L, but not RPL39L, is also expressed at higher level in cow. In chicken, another non-canonical RP gene paralog, RPL22L1, is specifically expressed in testis. Skeletal muscle samples exhibit a striking up-regulation of the non-canonical RP gene paralog RPL3L across all five species

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