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Fig. 2 | Genome Biology

Fig. 2

From: Patterns of ribosomal protein expression specify normal and malignant human cells

Fig. 2

Several RPs exhibit tissue-specific expression. a Heatmap depicting the standard score-normalized expression level of 90 RP genes across 28 human tissues. Genes encoding the same RP (paralog genes) can be classified into canonical (e.g., because they are more ubiquitously expressed) and non-canonical and are highlighted in blue and red, respectively. RP genes exhibiting tissue-specific expression are marked with a star. b Boxplots illustrating the distribution of specificity scores for each RP across tissues. Boxes extend from the 25th to 75th percentiles (interquartile range (IQR)), vertical lines represent the median, whiskers indicate the lowest and highest datum within 1.5*IQR from the lower and upper quartiles, respectively. Values outside this range are plotted as individual dots. Dotted lines show the thresholds defining tissue-specific RPs (|specificity score| >2.5). RPs are shown in the same order as in panel a

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