From: Choosing panels of genomics assays using submodular optimization
Choice | Histone | Association | Singleton | Objective | Objective loss |
---|---|---|---|---|---|
order | modification | score | gain | if swapped in | |
1 | H3K4me3 | Promoters | 3.18 | 3.18 | |
2 | H3K79me2 | Transcription | 2.40 | 0.97 | |
3 | H3K9me3 | Constitutive heterochromatin | 0.70 | 0.34 | |
4 | H3K27me3 | Facultative heterochromatin | 0.86 | 0.25 | |
5 | H3K36me3 | Transcription | 1.21 | 0.23 | |
6 | H3K4me1 | Enhancers | 1.86 | 0.18 | 0.05 (H3K36me3) |
7 | H3K4me2 | Regulatory | 3.12 | 0.08 | 0.07 (H3K36me3) |
8 | H3K9ac | Regulatory | 3.13 | 0.07 | 0.15 (H3K36me3) |
9 | H2A.Z | Promoters | 2.47 | 0.05 | 0.16 (H3K27me3) |
10 | H4K20me1 | Transcription | 1.41 | 0.005 | 0.22 (H3K36me3) |
11 | H3K27ac | Regulatory | 2.61 | 0 | 0.14 (H3K36me3) |