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Fig. 6 | Genome Biology

Fig. 6

From: Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells

Fig. 6

Self-representation in mTECs is expanded by extensive RNA processing. a Schematic representation of the comprehensive gene expression in the mTECs. These genes include many of the various tissue specific genes. All are further translated into antigens which are represented to T cells. b In this study, we further show very high levels of RNA editing and AS in mTECs. These RNA processes also result in tissue-specific antigens represented in mTECs

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Genome Biology

ISSN: 1474-760X

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