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Fig. 1 | Genome Biology

Fig. 1

From: A statistical approach for identifying differential distributions in single-cell RNA-seq experiments

Fig. 1

Schematic of the presence of two cell states within a cell population that can lead to bimodal expression distributions. a Time series of the underlying expression state of gene X in a population of unsynchronized single cells, which switches back and forth between a low and high state with means μ 1 and μ 2, respectively. The color of cells at each time point corresponds to the underlying expression state. b Population of individual cells shaded by expression state of gene X at a snapshot in time. c Histogram of the observed expression level of gene X for the cell population in (b)

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