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Table 1 Description of cohorts

From: An epigenetic clock for gestational age at birth based on blood methylation data

Dataset

N

GA range (weeks)

GA mean ± SD

Male (%)

Race

Nationality

Source

Array

Training datasets

GSE36642

51

32–38

36.3 ± 1.7

56.9

White

Australian

Cord

27 k

WMHP1

40

31–41

37.9 ± 2.3

47.5

98 % white

American

Cord

450 k

GSE62924

38

34–41

39.1 ± 1.4

42.1

White

Mexican

Cord

450 k

NBC

36

24–41

36.0 ± 5.4

47.2

Black

American

Cord

450 k

GSE51180

23

25–42

32.7 ± 6.6

69.6

White

Australian

Spot

450 k

GSE30870

19

34–41

38.9 ± 2.1

NA

White

Spanish

Cord

450 k

Test datasets

DNSBtrios

264

28–44

40.3 ± 1.9

64.9

White

Danish

Spot

450 k

WMHP2

251

33–43

38.7 ± 1.4

51.0

80 % white

American

Cord

27 k

CANDLE

198

32–41

39 ± 1.3

52.0

51 % black, 40.4 % white

American

Cord

27 k

VICS

183

24–35

28.0 ± 2.1

42.1

89 % white

Australian

Spot

450 k

PROGRESS

148

30–43

38.6 ± 1.7

52.0

White

Mexican

Cord

450 k

PREDO

91

31–42

39.6 ± 1.5

54.9

White

Finnish

Cord

450 k

  1. Training datasets and test datasets were chosen to represent a similar range of gestational ages
  2. NA not available, SD standard deviation