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Fig. 5 | Genome Biology

Fig. 5

From: Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

Fig. 5

Overview of approach and assessment of DNA methylation at distal regulatory elements defined using ENCODE DNAse hypersensitivity data. a Outline of the approach taken to analyse the relationship between DNAse hypersensitivity and DNA methylation in LNCaP and PrEC cell lines, using a schematic representation of the genome. b Venn diagram showing the sites that were informative in PrEC WGBS and EPIC methylation data at ENCODE reference distal DHS sites. c, d Methylation status of DNAse sensitive and non-sensitive sites according to c) WGBS and d) EPIC PrEC methylation data

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