Fig. 6
From: Correlation of an epigenetic mitotic clock with cancer risk
epiTOC’s tick rate is increased in buccal tissue from smokers. a Density scatterplot of pcgtAge (y-axis) versus smoking pack-years for a total of 647 buccal samples from women all aged 53 years at the time of sampling. Pearson correlation coefficient (PCC) and one-tailed P value from a linear regression are given. b As a but for Horvath’s age-acceleration measure. c Density scatterplot of pcgtAge (y-axis) in whole blood (WB) versus pcgtAge in buccal (BUC) tissue for a total of 152 women all aged 53 years who provided both a WB and a buccal sample. PCC and associated one-tailed P value are given. d Density scatterplots of pcgtAge in WB and BUC tissue against smoking pack years for 122 women with smoking pack year information. P values are from a one-tailed correlation test. e, f As c, d but for Horvath’s age acceleration measure. Note that because all samples are of the same age, the age-acceleration measure is just a constant shift of the predicted DNAm age