Fig. 7

Distances of rare and frequent high-survival-impact gene CNAs from genomic features. Selected examples for LUAD, GBM, and OV considering chromosomal distances of all gene CNAs with a high impact on cohort-specific survival signature genes from genomic features. See Additional file 1: Figure S21 for distance distributions of all tumor cohorts. a Distances of rare and frequent LUAD gene CNAs from known oncogenes. b Distances of rare and frequent LUAD gene CNAs from known essential genes. c Distances of rare and frequent LUAD gene CNAs from known tumor suppressor genes. d Distances of rare and frequent GBM gene CNAs from known fragile sites. e Distances of rare and frequent GBM gene CNAs from known frequently occurring germ-line CNVs. f Same as (e), but for OV. Significant differences in distances of rare and frequent CNAs from genomic features are represented by * (p<0.05) and ** (p<0.01, Wilcoxon test). CNA copy number alteration, GBM glioblastoma multiforme, LUAD lung adenocarcinoma, OV ovarian serous cystadenocarcinoma