TY - JOUR AU - Beaumont, Michelle AU - Goodrich, Julia K. AU - Jackson, Matthew A. AU - Yet, Idil AU - Davenport, Emily R. AU - Vieira-Silva, Sara AU - Debelius, Justine AU - Pallister, Tess AU - Mangino, Massimo AU - Raes, Jeroen AU - Knight, Rob AU - Clark, Andrew G. AU - Ley, Ruth E. AU - Spector, Tim D. AU - Bell, Jordana T. PY - 2016 DA - 2016/09/26 TI - Heritable components of the human fecal microbiome are associated with visceral fat JO - Genome Biology SP - 189 VL - 17 IS - 1 AB - Variation in the human fecal microbiota has previously been associated with body mass index (BMI). Although obesity is a global health burden, the accumulation of abdominal visceral fat is the specific cardio-metabolic disease risk factor. Here, we explore links between the fecal microbiota and abdominal adiposity using body composition as measured by dual-energy X-ray absorptiometry in a large sample of twins from the TwinsUK cohort, comparing fecal 16S rRNA diversity profiles with six adiposity measures. SN - 1474-760X UR - https://doi.org/10.1186/s13059-016-1052-7 DO - 10.1186/s13059-016-1052-7 ID - Beaumont2016 ER -