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Fig. 5 | Genome Biology

Fig. 5

From: An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation

Fig. 5

Co-localization of genome-wide association study (GWAS) signals associated with both schizophrenia and DNA methylation in blood and brain. Manhattan plots illustrate the location of genetic variants (x-axis) and their significance (y-axis; −log10 scale) in GWAS of schizophrenia (a), and DNA methylation at cg24592962 in blood (b) and brain (c). The solid red line indicates the location of the DNA methylation site (cg24592962). Comparing the pattern of these results for the mQTL and schizophrenia is supportive of the same causal variant being associated with both. Other examples are presented in Additional file 4

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Genome Biology

ISSN: 1474-760X

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