Fig. 3

There is minimal overlap between significant schizophrenia-associated differentially methylated positions and those associated with the schizophrenia polygenic risk score (PRS). Shown is a scatterplot comparing probe-wise significance in the epigenome-wide association study (EWAS) of schizophrenia case status (x-axis) and PRS (y-axis). Data are presented for probes identified as significant (P < 5 × 10⁻⁵) in the schizophrenia EWAS (red circles), PRS EWAS (blue triangles), or both (green diamonds)