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Fig. 5 | Genome Biology

Fig. 5

From: Integrative epigenomic analysis reveals unique epigenetic signatures involved in unipotency of mouse female germline stem cells

Fig. 5

Prmt5 is involved in FGSC biology. a Immunostaining of Prmt5 (green) in FGSCs. Nuclei were counterstained with DAPI (blue). Scale bar, 10 μm. b Quantitative RT-PCR analysis of meiosis-related genes in Prmt5 knockdown FGSCs. Relative expression levels were normalized to the control. Error bars indicate standard deviations of three biological replicates. c Scatter plot of RNA-Seq reads in control (x-axis) and Prmt5 knockdown (y-axis) cells. Red dots indicate genes that are up-regulated in Prmt5 knockdown FGSCs. d GO analysis of up-regulated genes in Prmt5 knockdown FGSCs (p < 0.05)

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