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Fig. 2 | Genome Biology

Fig. 2

From: Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability

Fig. 2

Senescence-associated heterochromatic foci (SAHF) are enriched for H4K20me3. a Immunofluorescent images of control (CON) and OIS cells co-stained with antibodies against H4K20me3 and PML. b Cells from a stained with antibodies to H4K20me3 and 53BP1. c Cells from a stained with antibodies to H4K20me3 and γ-H2AX. d Cells from a co-stained with 4′,6-diamidino-2-phenylindole (DAPI) and an antibody against H4K20me3. e Linescan intensity analysis of H4K20me3 and DAPI fluorescence intensity profiles along the arrows indicated in d. f Cells from a stained with antibodies to H4K20me3 and H3K9me3 and DAPI. g Linescan intensity analysis of H4K20me3 and H3K9me3 and DAPI fluorescence intensity profiles along the arrow indicated in f

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Genome Biology

ISSN: 1474-760X

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