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Fig. 2 | Genome Biology

Fig. 2

From: The mRNA-bound proteome of the human malaria parasite Plasmodium falciparum

Fig. 2

Relative abundance of mRNA-binding domains in P. falciparum in comparison to other eukaryotes. a Percentage of proteins in the full proteome that contain an mRNA-binding domain (mRBD). Abbreviations are listed on the right. The presence (+) or absence (–) of RNA interference machinery is indicated at the bottom. b k-means clustering of mRBDs based on relative abundance among all 11 organisms. The mRBD frequency in an organism was first normalized by proteome size and then scaled to the mRBD frequency in the organism with the highest relative abundance of that mRBD, which was given an arbitrary abundance value of 1. For clusters with unique enriched Gene Ontology (GO) terms associated with the Pfam domains (false discovery rate, FDR <0.01), a subset of these terms is shown on the right. See Additional file 4 for the full data set. c Selection of mRBDs that are relatively enriched in P. falciparum as compared to all or select groups of other eukaryotes. The cluster that these mRBDs fall into is indicated on the right. d Selection of mRBDs that are relatively depleted in P. falciparum as compared to all or select groups of other eukaryotes

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