Skip to main content

Table 1 Characteristics of the six cohorts in the BIOS Consortium

From: Blood lipids influence DNA methylation in circulating cells

  CODAM LL LLS NTR PAN RS
Number of individuals 164 748 785 692 184 723
RNA-Seqa 159 616 650    619
Gender (% male) 50 42 48 32 60 42
Age (years) [SD] 65.6 [6.8] 45.6 [13.3] 58.4 [7.5] 34 [12.1] 62.4 [9.4] 67.6 [6.0]
TG (mmol/L) [SD] 1.6 [0.8] 1.2 [0.9] 1.9 [1.2] 1.3 [0.7] 1.9 [1.1] 1.5 [0.9]
LDL-C (mmol/L) [SD] 3.6 [1.0] 3.0 [0.9] 3.4 [1.0] 2.8 [0.8] 3.4 [0.9] 3.3 [0.9]
HDL-C (mmol/L) [SD] 1.3 [0.3] 1.5 [0.4] 1.4 [0.4] 1.4 [0.9] 1.4 [0.4] 1.5 [0.4]
Monocytes (%) [SD] 7.9 [1.6] 8.5 [2.2] 5.5 [1.5] 7.7 [2.0] 6.8 [1.1] 7.1 [2.1]
Lymphocytes (%) [SD] 51.2 [14.0] 34.5 [7.4] 29.2 [6.9] 35.1 [7.8] 31.8 [7.1] 36.3 [7.9]
Neutrophils (%) [SD] 40.7 [6.9] 53.3 [8.0] 59.8 [7.7] 52.6 [7.7] 55.3 [7.0] 48.3 [7.1]
  1. aThe number of individuals for which RNA-Seq data were available
  2. CODAM Cohort on Diabetes and Atherosclerosis Maastricht, LL LifeLines, LLS Leiden Longevity Study, NTR Netherlands Twin Register, PAN Prospective ALS Study Netherlands, RS Rotterdam Study, SD standard deviation