Skip to main content

Table 1 Summary of functional assays results

From: Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma

#

Ensemble ID

Gene symbol

Viability (MTS)

Proliferation (IncuCyte)

Apoptosis (Caspase-3/7)

U251

U343

U251

U343

U251

U343

1

ENSG00000106305

AIMP2

✓

✓

-

-

-

-

2

ENSG00000183684

ALYREF

-

-

-

-

✓

-

3

ENSG00000179218

CALR

-

-

-

-

-

-

4

ENSG00000174371

EXO1

-

-

-

-

-

-

5

ENSG00000172183

ISG20

-

-

✓

-

-

-

6

ENSG00000162385

MAGOH

-

-

-

-

✓

-

7

ENSG00000111196

MAGOHB

-

-

-

-

✓

-

8

ENSG00000128626

MRPS12

-

-

-

-

-

-

9

ENSG00000090263

MRPS33

-

✓

-

✓

✓

-

10

ENSG00000132603

NIP7

✓

-

✓

✓

-

-

11

ENSG00000132661

NXT1

-

✓

✓

-

✓

-

12

ENSG00000111331

OAS3

-

-

-

-

-

-

13

ENSG00000171960

PPIH

-

-

-

-

-

-

14

ENSG00000153250

RBMS1

✓

✓

✓

✓

-

-

15

ENSG00000104889

RNASEH2A

✓

✓

✓

✓

✓

-

16

ENSG00000026297

RNASET2

-

-

-

-

-

-

17

ENSG00000175792

RUVBL1

✓

-

✓

-

✓

-

18

ENSG00000125835

SNRPB

✓

✓

✓

✓

✓

✓

19

ENSG00000143977

SNRPG

-

-

✓

-

✓

-

20

ENSG00000060138

YBX3

-

-

-

-

✓

-

21

ENSG00000088930

XRN2

-

✓

✓

-

-

-

  1. ✓ = significant difference compared to control (p-value < 0.05)
  2. - = no significant difference compared to control (p-value ≥ 0.05)