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Fig. 6 | Genome Biology

Fig. 6

From: Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma

Fig. 6

SNRPB impact on cancer genes and on alternative/constitutive exons/introns. a Sashimi plots highlighting two splicing events differentially regulated in siSNRPB compared with siCtrl: an exon skipping event in K-RAS (top panel) and an intron retention in H-RAS (bottom panel). b A total of 368 cancer genes were evaluated. Only genes presenting differential expression (upregulated or downregulated) or at least one splicing alteration [exon skipping (SE), mutually exclusive exons (MXE), alternative 5′ splice site (A5SS), alternative 3′ splice site (A3SS), or intron retention (RI)] are shown. c Alternative exons and introns are more affected by SNRPB knockdown than constitutive exons and introns

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Genome Biology

ISSN: 1474-760X

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