Fig. 8

Scope for utility of the DOG box to predict secretory proteins. a The number of promoter regions with multiple copies of DOG motifs is higher than random for G. rostochiensis, G. pallida and M. hapla, but not for B. xylophilus. Normal promoter regions are shown in red, 250 iterations of randomising the sequence of each promoter region are shown in grey, the average of which is shown in black. b For G. rostochiensis and G. pallida, the more motifs present in the promoter region, the more likely it is that the corresponding gene will contain a signal peptide for secretion (red line). Randomising each promoter region abolishes this effect (black line). For M. hapla and B. xylophilus, an increased number of motifs in the promoter regions does not correlate with a greater chance of the corresponding gene containing a predicted signal peptide