Fig. 7

DOG box: a six-nucleotide motif enriched in the promoter region of dorsal gland effectors. a The ATGCCA motif is specifically enriched in the promoter region of dorsal gland effectors compared to non-effectors and subventral gland effectors. On average, DOG box-containing dorsal gland effectors contain ~2.54 copies of the motif in their promoter region, compared to ~0.22 for an identical sized random subset of non-effectors or ~0.48 for subventral gland effectors. The frequency of this motif peaks 150 bp upstream of the start codon and is not strand-specific. b A strand-specific, Kozak-like motif, which includes the start codon (AAAATG), can be seen for dorsal, subventral and non-effectors at the predicted start of the coding sequence, indicating that predictions of translation start sites are accurate. No substantial cross-identification between each motif is seen