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Table 1 Hypergeometric probability calculations for the common changes defined using extremely low stringency (1.05-fold, P <0.05) detected in [2]

From: Response to “Variable directionality of gene expression changes across generations does not constitute negative evidence of epigenetic inheritance” Sharma, A. Environmental Epigenetics, 2015, 1-5

Number of genes (1.0 ST)

DEHP G1R (Iqbal)

DEHP G2R (Iqbal)

DEHP G1R-G2R (Iqbal)

Probability

21041

3639

1482

77 (same direction)

1

21041

3639

1482

248 (opposite direction)

0.73

21041

3639

1482

325 (both directions)

1.16E-06

Number of genes (1.0 ST)

VZ G1R (Iqbal)

VZ G2R (Iqbal)

VZ G1R-G2R (Iqbal)

Probability

21041

4295

1044

30 (same direction)

1

21041

4295

1044

254 (opposite direction)

8.94E-04

21041

4295

1044

284 (both directions)

4.04E-08

  1. https://www.geneprof.org/GeneProf/tools/hypergeometric.jsp
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Genome Biology

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