Fig. 3
From: SLICER: inferring branched, nonlinear cellular trajectories from single cell RNA-seq data
Synthetic data example showing that SLICER can detect branches and bubbles. a Three simulated genes showing the bubble structure. b Geodesic entropy computed for the trajectory (top) and recursively for the longest branch (bottom). The dotted line in each plot represents an entropy of 1, which indicates the beginning of a branch. c LLE embedding with branches colored. Black is the initial path that splits into two branches (red and blue). The shorter arm of the initial branch then branches again (yellow and green) at the end of the bubble. d Plot showing the boundaries of the bubble (blue) as detected by SLICER