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Table 3 Protein-related fields reported by the VEP
| Property | Description |
|---|---|
| Protein ID | Ensembl stable identifier for affected protein product |
| RefSeq ID | NCBI RefSeq identifier for affected protein |
| SWISSPROT ID | Manually curated protein identifier from UniProt |
| TrEMBL ID | Automatically generated identifier from UniProt |
| UniParc ID | Combined protein identifier from UniProt |
| Protein coordinates | Coordinates of input variant in protein product |
| Codons | Reference and alternative codons as generated by input variant |
| Amino acids | Reference and alternative amino acids as generated by input variant |
| SIFT | SIFT pathogenicity prediction and score |
| PolyPhen | PolyPhen-2 pathogenicity prediction and score |
| Protein domains | Protein domains overlapping input variant |
| HGVS | HGVS notations for input variant relative to the protein sequence |
