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Fig. 3 | Genome Biology

Fig. 3

From: Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

Fig. 3

Single-cell sequencing analysis confirms both recurrent chromosome copy numbers and karyotype heterogeneity in CIN T-ALLs. a Kaplan-Meier survival curve of the listed genotypes. T-ALLs that were single-cell sequenced in this study are indicated with a black arrow and tumour ID. b Thymic/T-ALL weights of the listed genotypes. T-ALLs indicated in red were analysed using single-cell sequencing. c–h Genome-wide copy number plots as generated by the AneuFinder algorithm for six samples: one Lck-Cre− control thymus and five CIN-driven T-ALLs. Individual cells are represented in rows, with the copy number state for ~1 Mb bins indicated in colours (see legend)

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