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Table 2 Number of SNV and short insertion/deletion mutations in the sequenced samples

From: A comprehensive survey of the mutagenic impact of common cancer cytotoxics

Treatment n SNV Insertion Deletion
Mean ± SD Mean ± SD Mean ± SD
None (starting clone) 1 0 0 0
Mock 4 47 ± 20 4.5 ± 1.3 3.0 ± 0.8
Cisplatin 3 812 ± 193 49.0 ± 15.0 83.0 ± 21.2
Cyclophosphamide 3 254 ± 50 3.0 ± 1.7 5.0 ± 1.7
Hydroxyurea 3 74 ± 9 4.7 ± 1.5 3.7 ± 1.2
Gemcitabine 3 57 ± 31 2.3 ± 2.1 3.0 ± 1.7
5-fluorouracil 3 50 ± 16 3.0 ± 1.0 2.7 ± 1.5
Etoposide 3 95 ± 15 3.7 ± 1.2 6.7 ± 4.2
Doxorubicin 3 44 ± 15 3.3 ± 0.6 4.0 ± 4.6
Paclitaxel 3 64 ± 10 1.0 ± 1.0 3.0 ± 0.0