Fig. 2From: RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells a ES cell in vitro neuralization and RNA analysis. DIV days of in vitro differentiation. b The fraction of total mRNAs that are up- or down-regulated between consecutive steps of differentiation, with a threshold of |log2FC| > 2.5 (where FC is fold change). c Number of genes whose mRNA is significantly released (or loaded) by Argonaute (Ago; see “Methods”); ***p = 0.001 (χ2-test). IP immunoprecipitationBack to article page