Fig. 4

Assembly improvements on sequenced genomes using OPERA-LG. a Results for the M. undulatus genome, comparing OPERA-LG against the best assemblers in the ASSEMBLATHON2 competition (in blue) and standalone scaffolders (in black; SOPRA did not complete after 10 days of runtime). Note that while OPERA-LG’s original N50 is similar to that of other methods, its corrected N50 is >1.5× that of others. Scatter plot of incorrect joins and corrected N50 for b S. aureus, c P. falciparum, and d H. sapiens chromosome 14. OPERA-LG is consistently among the top three methods in terms of corrected N50 in this evaluation. e Assembly augmentation using OPERA-LG for the C. sinenis and CHO-K1 genomes significantly boosts assembly contiguity