Fig. 4

Correlation of gene body methylation with gene expression in a single neuron. a Scatter plot of gene body methylation and transcription level for genes within single neuron cells. b Dot plot of Pearson correlation coefficients between transcription level (as expression percentile) and gene body methylation. The genes with CpG sites detected in the region more than 0.5 Kb were clustered into two groups, CGI promoter genes and non-CGI promoter genes. c, d Representative scatter plot examples of the CGI promoter genes which are expressed and positively correlated with gene body methylation. *p <0.0001 (Student’s t-test)