Fig. 3From: Epigenetic assimilation in the aging human brainUnsupervised hierarchical clustering of DNA modification in the brains of EAO and LAO AD twins. a The red boxes indicate clades with higher than 80Â % bootstrapping probability. Clustering, using the top 5Â % of the most differentially modified loci, showed that cerebellum (CB) and EAO cerebral cortex form a single clade 95Â % of the time while the cortex from the LAO co-twins are in a separate clade 95Â % of the time. b In the top 82Â AD onset-associated loci, the cerebral cortex of EAO twins and the cerebellum clustered into a single clade 98Â % of the time, while LAO co-twins separated into a different clade 98Â % of the timeBack to article page