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Fig. 3 | Genome Biology

Fig. 3

From: Epigenetic assimilation in the aging human brain

Fig. 3

Unsupervised hierarchical clustering of DNA modification in the brains of EAO and LAO AD twins. a The red boxes indicate clades with higher than 80 % bootstrapping probability. Clustering, using the top 5 % of the most differentially modified loci, showed that cerebellum (CB) and EAO cerebral cortex form a single clade 95 % of the time while the cortex from the LAO co-twins are in a separate clade 95 % of the time. b In the top 82 AD onset-associated loci, the cerebral cortex of EAO twins and the cerebellum clustered into a single clade 98 % of the time, while LAO co-twins separated into a different clade 98 % of the time

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