Fig. 1
ICC analysis of DNA modification and gene transcription within the cerebral cortex and the cerebellum. The histograms represent the densities of the permuted mean ICC coefficients from samples of all ages and the red dashed lines show the mean ICC in the older individuals (>75 years). a Mean ICC of DNA modification in the cerebral cortex of older individuals (permuted p = 7 × 10−6). b Mean ICC of DNA modification in the cerebellum of older individuals (permuted p = 9 × 10−4). c Mean ICC of the transcriptome in the cerebral cortex of older individuals (permuted p = 5 × 10−6). d Mean ICC of the transcriptome in the cerebellum of older individuals (permuted p < 10−6)