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Table 8 Performance metrics under simulation scenario 6 (continuous)

From: An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies

Method Number of false positives Power KS GIF \(\hat {K}\)
Unadjusted 135 0.532 0.081 1.37
Ref-based 13 0.498 0.031 0.99
Ref-free 125 0.618 0.061 1.17 14
SVA 29 0.502 0.006 0.99 10
ISVA 114 0.520 0.076 1.21 14
CellCDec 422 0.420 0.079 1.44
Deconf a
RUV 16 0.550 0.006 0.966 39
  1. KS Kolmogorov–Smirnov statistic, GIF genomic inflation factor
  2. aNo results were obtained with K=3 in the allowable time on the computational cluster Mammouth