Table 8 Performance metrics under simulation scenario 6 (continuous)
From: An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies
Method | Number of false positives | Power | KS | GIF | \(\hat {K}\) |
|---|---|---|---|---|---|
Unadjusted | 135 | 0.532 | 0.081 | 1.37 | – |
Ref-based | 13 | 0.498 | 0.031 | 0.99 | – |
Ref-free | 125 | 0.618 | 0.061 | 1.17 | 14 |
SVA | 29 | 0.502 | 0.006 | 0.99 | 10 |
ISVA | 114 | 0.520 | 0.076 | 1.21 | 14 |
CellCDec | 422 | 0.420 | 0.079 | 1.44 | – |
Deconf a | – | – | – | – | – |
RUV | 16 | 0.550 | 0.006 | 0.966 | 39 |