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Table 1 Number of mQTL and associated CpGs reaching the significance threshold for each time point

From: Systematic identification of genetic influences on methylation across the human life course

Counts

Birth

Childhood

Adolescence

Pregnancy

Middle age

Sentinel mQTL

     

  Cis a

24,262

31,729

30,294

29,038

27,043

  Trans b

1979

2658

2442

2394

2144

Conditionally independentc

2705

5446

5040

4454

3463

Total mQTL

28,946

39,833

37,776

35,886

32,650

Total unique CpGs

27,387

36,705

34,886

33,344

30,676

  1. aNumber of CpG sites with a cis SNP
  2. bNumber of independent (±1 Mb) trans effects
  3. cNumber of mQTL further detected after performing conditional analysis