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Fig. 1 | Genome Biology

Fig. 1

From: Pro-inflammatory miR-223 mediates the cross-talk between the IL23 pathway and the intestinal barrier in inflammatory bowel disease

Fig. 1

The pathological role of the IL23/Th17 pathway in TNBS-induced colitis. a Recovery of body weight in mice with TNBS-induced colitis by anti-IL23P19. Control: colitis mice treated with ethanol; TNBS + P19: TNBS-induced colitis mice treated with an IL23 antibody; TNBS + ISO: TNBS-induced colitis mice treated with an isotype control; *P <0.05, **P <0.01, ***P <0.001 for comparison between the TNBS + ISO and the Ethanol Control; # P <0.05 for the statistical significance between the TNBS + P19 treatment group and the TNBS + ISO control group. b Representative images of the colon in treated mice with colitis. c Representative cross-sections of the transverse colon. Magnification of the images is 200-fold. d Anti-IL23P19 therapy reduces the histological score. *P <0.05 as compared with the TNBS + ISO control group. e Serum FITC-dextran was quantified as a measure of intestinal permeability. **P <0.01 as compared with the TNBS + ISO control group. f Effects on MPO activity measurement by Anti-IL23P19. *P <0.05 as compared with the TNBS + ISO control group

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Genome Biology

ISSN: 1474-760X

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