Fig. 1From: Polycomb-mediated chromatin compaction weathers the STORMEpigenetically defined chromatin states have distinct conformations. Three chromatin domains identified in Drosophila nuclei are characterized epigenetically and functionally as polycomb-repressed, transcriptionally active and transcriptionally inactive (top). Repressed domains are the most compact and have minimal contact with other domains, properties that are lost upon disruption of polycomb repressive complex 1 (PRC1), which results in the activation of repressed genes (bottom). Ph polyhomeoticBack to article page