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Fig. 1 | Genome Biology

Fig. 1

From: Trapping the intruder — immune receptor domain fusions provide new molecular leads for improving disease resistance in plants

Fig. 1

Comparison of different effector recognition models by intracellular plant nucleotide-binding, leucine-rich repeat (NLR) immune receptors. In the guard model, NLR receptors perceive modifications in guardees that are introduced by microbial effector proteins. Guardees often have a function in basal plant defense and they are therefore frequently targeted by effectors. The decoy is a duplicated guardee without a function in plant immunity. Its sole role is to trap effectors, thereby activating the immune signaling cascade. The guardee or decoy and the monitoring NLR are often encoded by different genes that likely bind to each other, but can dissociate. The integrated domain model involves a fusion between the decoy domain and the respective NLR, which together are encoded by one gene

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