Skip to main content


Fig. 2 | Genome Biology

Fig. 2

From: MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data

Fig. 2

Single-cell expression (log2-transcripts per million) of the top 100 genes identified as differentially expressed between cytokine (IL18, IL15, IL12)-stimulated (purple) and non-stimulated (pink) MAIT cells using MAST (a). Partial residuals for up-regulated and down- regulated genes are accumulated to yield an activation score (b), and this score suggests that the stimulated cells have a more heterogeneous response to stimulation than do the non-stimulated cells

Back to article page