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Table 1 Summary statistics for number of findings by analysis category

From: High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction

  Local (≤1 Mb) Distant same chromosome (>1 Mb) Cross-chromosome Total
Part I: overall findings     
Number of tests (billions) 16.7 1140.2 19,440.1 20,597.0
Fraction of tests significant at FDR = 1 % 4 × 10−3 3.7 × 10−7 7 × 10−10
P value threshold for FDR = 1 % 4.05 × 10−5 3.74 × 10−9 7.03 × 10−12
Number of tests significant at FDR = 1 % 67,752,610 426,958 13,672
Number of unique SNPs with meQTLs 4,426,992 (97.68 %) 36,916 (0.81 %) 11,204 (0.25 %) 4,532,060
Unique methylation sites with meQTLs 683,152 (15.03 %) 3819 (0.08 %) 286 (0.01 %) 4,544,738
Part II: by methylation site features     
At MAF ≥ 0.05     
Sites (with meQTLs) 683,152 3,819 286 4,544,738
With CpG-SNPs 75 % 45 % 35 % 33 %
With other SNPs 12 % 18 % 20 % 30 %
Without SNPs 13 % 37 % 45 % 37 %