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Fig. 2 | Genome Biology

Fig. 2

From: Identification of low abundance microbiome in clinical samples using whole genome sequencing

Fig. 2

False bacteria identifications are readily identified by a drop in the number of mapped reads after filtering human sequences and inconsistent coverage. a Log-transformed counts per million (CPM) reads mapped to Candidatus Zinderia insecticola after each filtering step for each sample as outlined in Fig. 1. b Reads coverage map of Candidatus Zinderia insecticola in sample 10-Antrum-B1 after all filtering steps. Points represent the read counts in a 5-kb window. c Log-transformed CPM mapped to Thermoanaerobacter wiegelii after each filtering step for each sample. d Similar to (b), reads coverage map of Thermoanaerobacter wiegelii in sample 10-Antrum-B1. After all filtering steps, the coverage map indicates that reads map to only a single region of the genome. BWA Burrows-Wheeler Aligner

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