Table 2 Top 2 annotation clusters enriched in proestrus versus males
Cluster enrichment score | Term | Count | p-value | Fold enrichment |
|---|---|---|---|---|
Cluster #1: 1.45 | Negative regulation of transcription, DNA-dependent | 5 | 5.41E−03 | 6.55 |
|  | Negative regulation of RNA metabolic process | 5 | 5.71E−03 | 6.45 |
|  | Negative regulation of transcription | 5 | 1.20E−02 | 5.20 |
|  | Negative regulation of transcription from RNA polymerase II promoter | 4 | 1.51E−02 | 7.22 |
|  | Negative regulation of gene expression | 5 | 1.61E−02 | 4.77 |
|  | Negative regulation of nucleobase, nucleoside, nucleotide, and nucleic acid metabolic process | 5 | 1.73E−02 | 4.68 |
|  | Negative regulation of nitrogen compound metabolic process | 5 | 1.82E−02 | 4.60 |
|  | Negative regulation of macromolecule biosynthetic process | 5 | 2.09E−02 | 4.42 |
|  | Negative regulation of cellular biosynthetic process | 5 | 2.23E−02 | 4.33 |
|  | Negative regulation of biosynthetic process | 5 | 2.41E−02 | 4.23 |
|  | Negative regulation of macromolecule metabolic process | 5 | 5.54E−02 | 3.25 |
|  | Regulation of transcription from RNA polymerase II promoter | 4 | 1.48E−01 | 2.85 |
|  | Transcription | 4 | 2.03E−01 | 2.45 |
|  | Regulation of transcription, DNA-dependent | 5 | 2.23E−01 | 1.96 |
|  | Regulation of RNA metabolic process | 5 | 2.40E−01 | 1.90 |
|  | Regulation of transcription | 6 | 2.41E−01 | 1.70 |
Cluster #2: 0.57 | Regulation of growth | 3 | 1.57E−01 | 4.04 |
|  | Negative regulation of apoptosis | 3 | 1.78E−01 | 3.74 |
|  | Negative regulation of programmed cell death | 3 | 1.81E−01 | 3.70 |
|  | Negative regulation of cell death | 3 | 1.82E−01 | 3.68 |
|  | Regulation of apoptosis | 3 | 4.74E−01 | 1.82 |
|  | Regulation of programmed cell death | 3 | 4.81E−01 | 1.80 |
|  | Regulation of cell death | 3 | 4.83E−01 | 1.79 |