Table 1 A comparison of HiC Analysis software algorithms and features
From: HiFive: a tool suite for easy and efficient HiC and 5C data analysis
| Method | Normalization algorithm | Can account for distance | Fend-level resolution | Parallelizable |
|---|---|---|---|---|
| HiFive | Matrix balancing | X | X | X |
| Binning | X | X | X | |
| Probability | X | X | X | |
| HiCPipe | Binning | X | X | |
| HiCNorm | Poisson regression | |||
| HiCLib | Matrix balancing | X | ||
| HiTCa | Poisson regression | |||
| Matrix balancing | X | |||
| HOMER | Read coverage | X | X | |
| Hi-Corrector | Matrix balancing | X | X |