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Fig. 3 | Genome Biology

Fig. 3

From: gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens

Fig. 3

Gene-specific phenotypes (GSPs) estimated by gespeR are highly reproducible between different RNAi libraries across all pathogens. Mutual concordance is evaluated between phenotypes for the same genes. *Significantly better than second best method (Wilcoxon rank sum test, p < 0.05). a gespeR GSPs for four Qiagen genome-wide sub-libraries are significantly more reproducible than RSPs and estimates from haystack and RSA. b gespeR GSPs exhibit significantly stronger concordance than in silico pooled RSPs (ISPs) between single and pooled siRNA libraries from different vendors (Qiagen single-siRNA versus Dharmacon pooled)

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