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Fig. 4 | Genome Biology

Fig. 4

From: Schmutzi: estimation of contamination and endogenous mitochondrial consensus calling for ancient DNA

Fig. 4

Consensus call and contamination estimate accuracy for empirical datasets. a The htslib consensus call (yellow) and the schmutzi consensus call (red) were performed on a subset of the data from three Neanderthals, one Denisovan and one early modern human. The number of mismatches between the mitochondrial consensus sequence and the published mitochondrial genome from the same individual was calculated. b Contamination was estimated using schmutzi (red) and contamMix v.1.0-10 (blue) and compared to the contamination computed using diagnostic positions (gray per fragment and black per base). For the two Mezmaiskaya individuals, the endogenous genome used for comparison was obtained using another library with low levels of contamination from the same individual. diag pos diagnostic position, Nean Neanderthal

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