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Table 2 Co-localization of histone modifications with induced XIST RNA signal

From: Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST

Clone

H3K27me3

H4K20me1

macroH2A

SMCHD1

H2AK119u1

H3K9me3

1p

−

+/−

−a

−

+

−

3q

−

 

+a

−a

  

4q

+/−

−

+/−

−a

  

7p

+/−

+/−

+

+/−a

  

7q

+/−b

−b

−a

+/−

  

8p

+b

+/−b

+ a

+a

+

−

12q

+/−b

−a

+

+/−

+

−

15q

+/−

+/−

+/−

+/−

  

Xq

+

+b

+a

+

+

−

  1. aIn situ hybridization performed at least in duplicate
  2. bIn situ hybridization performed on two independent clones
  3. Co-localization of the histone modification with the XIST signal was counted in at least 30 cells. No co-localization (−) was <10 % co-localization; +/− was between 10 % and 25 % co-localization and + is assigned to integration sites with over 25 % co-localization