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Table 2 Co-localization of histone modifications with induced XIST RNA signal

From: Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST

Clone H3K27me3 H4K20me1 macroH2A SMCHD1 H2AK119u1 H3K9me3
1p +/− a +
3q   +a a   
4q +/− +/− a   
7p +/− +/− + +/−a   
7q +/−b b a +/−   
8p +b +/−b + a +a +
12q +/−b a + +/− +
15q +/− +/− +/− +/−   
Xq + +b +a + +
  1. aIn situ hybridization performed at least in duplicate
  2. bIn situ hybridization performed on two independent clones
  3. Co-localization of the histone modification with the XIST signal was counted in at least 30 cells. No co-localization (−) was <10 % co-localization; +/− was between 10 % and 25 % co-localization and + is assigned to integration sites with over 25 % co-localization